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Handmade African American Reborn Baby Doll Eyes Closed
★A REALISTIC NEWBORN BABY APPEARANCE—His skin,moist lip, hand painted fingernails and toenails , even facial expression.All these details are very similar with real infants.
★WEIGHTED BODY MAKES “A TRULY REAL BABY” FEEL—The doll's body is cloth body which is soft and weighty. So he feels like a real baby in your arms.
★THE DOLL IS SAFE AND NON-TOXIC—Adopt Environmental friendly material so that your baby could gnawing bite on the doll safely. Makes a pure environment for your baby playing.
★ARMS AND LEGS ARE MOVABLE—Limbs can be moved up and down easily.He can do a lot of poses like crawling,sitting and lying.
★CLOTHES ARE REPLACEABLE—The doll will come with the clothes. You can change clothes for him and 0-3month old baby's clothes suit him.Also, there are different styles of clothes specialy designed for this doll in our store.
★A PERFECT CHOICE FOR YOUR BABY—He will be a good partner even during your baby sleeping.AS a nurturing doll which will improve your kids creativity ability.
●Material : Silicone vinyl head ,3/4 silicone vinyl limbs,cloth body of reborn baby is filled with soft natural environmentally friendly PP cotton,no gender,weighted hip.Baby doll is not waterproof,can't bath in water.
●Eyes: Can't open.
●Hair: Handmade rooted mohair.Can be washed.
1 x Reborn baby doll
1 x Doll outfit
1 x Pacifier
1 x Doll bottle
1 x Birth certificate
◆He will bring you a lot of fun and be one member of your family! Wish you love him!
◆We also have other reborn babies in our store ,welcome to choose!
Molecular pathway of estrogen receptor (ER) action. Typically, estrogen binds to the ligand-binding domain of receptors in the nucleus, which causes a conformational change. Estrogen-responsive elements (ERE) mediate genomic effects. RE, response element; TF, transcription factor; GF, growth factor; GF-R, growth factor receptor; CoA, co-activator; CoR, co-repressor; MAPK, mictogen-activated protein kinase; PI3K, phophoinositide 3-kinase; Src, proto-oncogene tyrosine-protein kinase; AP-1, activating protein-1; Sp-1, stimulating protein-1. Adapted from Nie et al.16
Measurement parameters utilized to determine the esophageal motor function. (A) Esophagogastric junction (EGJ). (B) Esophageal body. EGJ-CI, esophagogastric junction-contractile integral; IRP, integrated relaxation pressure; LES, lower esophageal sphincter.
High-resolution manometry test swallows and maneuvers. (A) Supine 5 mL liquid; (B) upright 5 mL liquid; (C) viscous (apple sauce); (D) solid (graham cracker); (E) multiple rapid swallow; and (F) rapid drink challenge. Integrated relaxation pressure (IRP) and distal contractile integral (DCI) were 11 mmHg and 1760 mmHg·cm·sec (A), 8 mmHg and 1950 mmHg·cm·sec (B), 7 mmHg and 1600 mmHg·cm·sec (C), 10 mmHg and 1400 mmHg·cm·sec (D), 4 mmHg and 4600 mmHg·cm·sec (E), and 3 mmHg and 0 mmHg·cm·sec (F), respectively. Figure used with permission from the Esophageal Center at Northwestern.
Our diagnostic algorithm of defecation disorders using a colonic transit study. DD, defecation disorders; DRE, digital rectal examination; NTC, normal transit constipation; STC, slow transit constipation; RS, rectosigmoid colon.
Statistical maps showing voxel-mirrored homotopic connectivity (VMHC) differences between irritable bowel syndrome (IBS) and healthy controls (HCs;